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INCLUSION BODY MYOSITIS

Rheumatology

INCLUSION BODY MYOSITIS

1. Most common inflammatory myopathy in persons > 50 years of age, more common in Caucasian men.

2. Indolent disorder characterized by prominent asymmetric distal weakness (weak handshake), dysphagia (leading to aspiration).

3. Risk factors - antimalarials, glucocorticoids, colchicine, statins, cocaine and alcohol use.

4. CK is only mildly elevated, muscle bx is diagnostic.

5. Take patients off the precipitating drugs and give a trial of steroids. Only minimally responsive to treatment.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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