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SJOGREN'S SYNDROME

Rheumatology

SJOGREN'S SYNDROME

Mucus glands are infiltrated by lymphocytes and plasma cells leading to atrophy and fibrosis.
1. Dry eyes - conjunctivitis, corneal ulcers.
2. Dry mouth.
3. Chest infection - due to reduced mucus production.
4. Kidneys - RTA, nephrogenic DI.
5. Genital tract - atrophic vaginitis.
6. Pseudolymphoma - lymphadenopathy and splenomegaly which can progress to non-Hodgkin's lymphoma.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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