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CPPD DEPOSITION DISEASE

Rheumatology

CPPD DEPOSITION DISEASE

1. Most idiopathic CPPD deposition occurs in patients > 65 years of age and who have underlying joint damage from OA or trauma.

2. When in a patient < 50 years of age, consider: primary hyperparathyroidism, hypomagnesemia, hypophosphatemia, haemochromatosis, hypothyroidism.

3. Presentation ranges from asymptomatic deposition to pseudogout.

4. Chondrocalcinosis is calcification of cartilaginous tissue and is a hint to underlying CPPD.

5. CPPD arthropathy usually affects the knee. Others include wrists, 2 nd & 3 rd MCPJ, shoulders, elbows, and ankles.

6. Look out for the patient with wrist arthritis with Bouchard (PIP) and Heberden (DIP) nodes - screen for hemochromatosis, hyperparathyroidism, and hypothyroidism in patients < 50 years.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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