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1. Refers to a condition in which the pressure within a given muscle compartment is abnormally elevated.

2. Acute compartment syndrome is usually caused by significant trauma, such as a fracture or crush injury, and is a surgical emergency.

3. Chronic exertional compartment syndrome (CECS) of the lower limb is seen most commonly in high-volume runners.

4. Patients C/O  recurrent leg cramping or pain with activities. Symptoms usually come on at a predictable time point in their exercise routine.

5. Ischemic neuropathy from high compartment pressures can occur.

6. Dx: pre-exercise pressure ≥15 mmHg, one-minute post exercise pressure ≥30 mmHg, five-minute post exercise pressure ≥20 mmHg. Tx: conservative (massage, analgesia, rest) vs. fasciectomy.


1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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