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RHEUMATOID ARTHRITIS-OTHER AGENTS

Rheumatology

RHEUMATOID ARTHRITIS-OTHER AGENTS

1. Leflunomide - pyrimidine antagonist and may be used as an initial DMARD in patients unable to take MTX. SE: diarrhea, respiratory infections, hepatotoxicity. Contraindicated in pregnancy.

2. Hydroxychloroquine - SE: retinopathy, patients require baseline optometry prior to commencing the drug.

3. Sulfasalazine - SE: sulfa-allergic reactions, nausea, vomiting, diarrhea, and crampy abdominal pain.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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