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DEMENTIA TYPE-DIFFUSE WHITE MATTER DISEASE

Neurology

DEMENTIA TYPE-DIFFUSE WHITE MATTER DISEASE

1. HTN & DM are common causes of dementia due to lacunar infarcts and diffuse white matter changes that are visible on MRI.

FEATURES
2. Early symptoms include mild confusion and impairments in memory, perception, and executive functions.

3. Marked difficulties in judgment and orientation develop later, along with dependence on others for ADLs.

4. Neuropsychiatric symptoms (apathy, anxiety, psychosis, euphoria, depression, aggression) also develop later.

5. Lastly, urinary incontinence and dysarthria with/without other pseudobulbar features (dysphagia, emotional lability) are frequent.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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