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COMA-METABOLIC ETIOLOGY

Neurology

COMA-METABOLIC ETIOLOGY

1. Causes - ischemia, hypoxia, hypoglycemia, thiamine deficiency (Wernicke's encephalopathy), organ disease (lung, liver, kidney), and drugs.

2. Early in metabolic encephalopathy, patients have changes in respiratory pattern and mentation.

3. The pupils are typically reactive until the terminal stages.

4. Exceptions include anticholinergic toxicity, which causes fixed dilated pupils, and severe barbiturate intoxication.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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