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CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY (CIDP)

Neurology

CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY (CIDP)

1. CIDP begins insidiously, progresses slowly and attains maximum severity after several months.

2. Chronic symmetric sensorimotor loss, EMG findings of demyelination, and elevated CSF protein, duration > 8 wks define the illness.

3. LP and EMG results are identical to GBS (high protein, no pleocytosis, and demyelinating polyneuropathy).

4. Exclude systemic disorders, specifically HIV, hepatitis viruses, Lyme, thyroid disease, diabetes, myeloma, sarcoid, and connective tissue disorders such as lupus.

5. Unlike in Guillain-Barre, glucocorticoids hasten recovery and prevent relapse in CIDP. Plasmapheresis or IVIG are also standard treatments.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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