Home
Radiology Guides Anatomy Physio & Path Medicine Physics Contact
CHARCOT-MARIE-TOOTH (CMT)

Neurology

CHARCOT-MARIE-TOOTH (CMT)

1. Motor and sensory neuropathy, is by far (90%) the most common inherited peripheral polyneuropathy.

2. There are 7 "types" composed of > 30 separate disorders, all caused by mutations in myelin genes that are variably inherited.

3. CMT diseases are demyelinating and are differentiated based on genetic markers, with sensory-motor impairment and present within the first 2 decades of life.

4. Diagnosis is with genetic testing and EMG/NCS is rarely required, treatment is supportive.


Avatar
REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

+ Home