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TRANSVERSE MYELITIS

Neurology

TRANSVERSE MYELITIS

1. TM is a rare problem causing inflammation of both sides of 1 or 2 segments of the cord (usually thoracic).

2. The exact cause is uncertain, but it appears to be an autoimmune reaction.

3. Onset typically follows a viral infection, but it is also associated with MS & several autoimmune disorders.

4. Clinical presentation is most often acute and progressive over a few days, with early paresthesias, bilateral leg weakness, and numbness with a sensory deficit below the level of the lesion, sphincteric disturbances and backache.

5.  A slight asymmetry of the symptoms and signs, a sensory level over the trunk, or a Babinski sign differentiate it from a rapidly progressive polyneuropathy such as GBS.

6. MRI with contrast shows the inflammation of the cord. CSF analysis shows increased protein, lymphocytosis, normal glucose.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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