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SEIZURE MANAGEMENT-PHENYTOIN

Neurology

SEIZURE MANAGEMENT-PHENYTOIN

1. Effective and well-tried, but no longer 1st line for generalized or partial epilepsy.

2. Toxicity - nystagmus, diplopia, tremor, dysarthria, ataxia.

3. SEs - decreased intellect, depression, coarse facial features, acne, gum hypertrophy, polyneuropathy, blood dyscrasias.

4. Increased clearance - OCP use, pregnancy.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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