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MYASTHENIA GRAVIS-TYPES

Neurology

MYASTHENIA GRAVIS-TYPES

1. Generalized MG presents as episodic weakness with repetitive movements, worse at end of day. Weakening with repetitive muscle stimulation during the physical exam (muscle fatigability) suggests the diagnosis.

2. Muscles of facial expression, mastication, swallowing, and speech are affected in 80% of patients at some time in the illness.

3. Ocular MG presents as weakness localized to the eyes (lids and extraocular muscles).

4. Differentiate from other forms of ptosis - demonstrate fatigable ptosis (i.e., worsening of ptosis on 30 seconds of sustained up gaze).


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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