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MYASTHENIA GRAVIS

Neurology

MYASTHENIA GRAVIS

1. Myasthenia gravis (MG) is an autoimmune disorder.

2. Most patients have autoantibodies to either the post-syn­aptic acetylcholine receptor or muscle-specific tyrosine kinase receptor (MuSK)!

3. An even smaller group of MG patients has neither anti-acetylcholine receptor nor anti­-MuSK antibodies (termed "seronegative MG").

4. MG is associated with thymomas (15% of patients) and thymic hyperplasia (60%).

5. Do a chest CT in patients with MG.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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