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LAMBERT-EATON SYNDROME-INVESTIGATION

Neurology

LAMBERT-EATON SYNDROME-INVESTIGATION

1. Voltage-gated calcium channel antibodies (anti-VGCC) - not 100% specific. Measure only in those with high pre-test probability.

2. EMG - decremental response (weakening) to rapid stimulation in MG and incremental response (strengthening) in LE syndrome.

3. Check for malignancy - SCC.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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