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ALCOHOLIC PERIPHERAL NEUROPATHY

Neurology

ALCOHOLIC PERIPHERAL NEUROPATHY

1. Alcohol is directly toxic to both nerves and muscles and causes many kinds of neuropathies (peripheral, autonomic, compressive).

2. The polyneuropathy is typically axonal but is made worse if demyelination is superimposed (caused by nutritional deficiencies).

3. Presents similar to diabetic neuropathy - with stocking-type numbness and loss of proprioception. Patients recover slowly with multivitamin therapy and alcohol abstinence.

4. Note: Acute thiamine deficiency presents as Wernicke's - polyneuropathy (weakness of extraocular muscles & ataxia) A/W delirium.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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