Home
Radiology Guides Anatomy Physio & Path Medicine Physics Contact
DIABETIC NEUROPATHY

Neurology

DIABETIC NEUROPATHY

1. Axonal neuropathy, mainly sensory changes, propriocpetion loss.

2. Diabetes can affect CN III (pupil sparing), IV, VI, VII, ulnar n. or peroneal n. Note - if there is CN III palsy with pupillary dilatation, think of a PCOM aneurysm.

3. Diabetic lumbosacral plexopathy (amyotrophy) presents with leg pain (82%) followed by proximal weakness of the leg. The condition develops over months and so does partial or complete recovery.

4. Effective treatments for pain include the FDA-approved duloxetine and pregabalin; others - tricyclic antidepressants, carbamazepine, gabapentin, lamotrigine, tramadol, and venlafaxine.

5. Metformin can lead to Vit B 12 malabsorption, leading to peripheral neuropathy.


Avatar
REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

+ Home