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ACUTE KIDNEY INJURY (AKI)-CANCER

Nephrology

ACUTE KIDNEY INJURY (AKI)-CANCER

1. Direct infiltration: by lymphoma, leukemia, or myeloma.

2. Obstruction: particularly from pelvic and abdominal tumors; intratubular uric acid obstruction due to tumor lysis syndrome, methotrexate crystallization.

3. Glomerular disease: minimal change disease Hodgkin disease), membranous GN (solid tumors), amyloidosis (multiple myeloma).

4. Chemotherapy drug toxicity: mitomycin C-induced hemolytic uremic syndrome; cisplatin-induced tubular injury.

5. Hypercalcemia: of malignancy can lead to acute renal failure.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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