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FRACTIONAL EXCRETION OF SODIUM

Nephrology

FRACTIONAL EXCRETION OF SODIUM

1. The fractional excretion of sodium (FE Na ) is the ratio of excreted Na + to the total filtered load of Na + .

2. It is used to differentiate prerenal azotemia (FE Na < I%, high levels of nitrogen-containing compounds such as creatinine and urea) from acute tubular necrosis (FE Na > 2%, ATN).

3. Other causes of AKI with FE Na < I% include: contrast­ induced ATN, cardio-renal syndrome, hepato-renal syndrome, non-oliguric ATN, pigment nephropathy & acute glomerulonephritis.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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