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ANALGESIC ABUSE NEPHROPATHY

Nephrology

ANALGESIC ABUSE NEPHROPATHY

1. Typically occurs in a patient with a history of frequent pain.

2. Presents with a low urine specific gravity, minimal proteinuria, sterile pyuria, and an elevated creatinine.

3. Papillary necrosis is the most common ultimate consequence.

4. A noncontrast CT of the kidneys may show the papillary necrosis.

5. Treatment is supportive, with discontinuation of offending analgesics.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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