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URINARY ANION GAP

Nephrology

URINARY ANION GAP

1. The Urine Anion Gap (UAG) is used to evaluate the etiology of normal AG metabolic acidosis to differentiate between GIT loss of HCO 3 - and RTA.

2. UAG is an estimate of unmeasured ions, particularly NH 4 + , expressed in mEq/L:

3. Normal value of UAG is close to 0.

4. A positive UAG value suggests low urinary NH 4 + which decreases Cl - in the urine (e.g., RTA Type 4).

5. A negative UAG value suggests high urinary NH 4 + which increases Cl - in the urine (e.g., diarrhea). Remember ne GUT ive UAG in cases of diarrhea.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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