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1. Proteinuria is an important indicator of underlying renal pathology; normal 24-hour urine protein is < 150 mg.

2. Greater than 2 g/d indi­cates significant glomerular pathology.

3. Medullary cystic disease and obstructive uropathy are the only exceptions in which there can be pathology and a normal urine sediment with minimal proteinuria.

4. Transient proteinuria is common in people during a febrile illness, after strenuous exercise, and in patients with HF and COPD.


1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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