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PRE-RENAL AKI-HEPATORENAL SYNDROME

Nephrology

PRE-RENAL AKI-HEPATORENAL SYNDROME

Criteria to establish a diagnosis of hepatorenal syndrome:

1. Cirrhosis with ascites and evidence of portal hypertension (ascites, splenomegaly, oesophageal varices, leukopenia, thrombocytopenia, anaemia)

2. A serum creatinine > 1.5mg/dL that progresses over days to weeks

3. Lack of improvement in renal function after withdrawal of diuretics and volume expansion with albumin (1 g/kg of body weight per day up to 100 g/day) for at least 2 days

4. No evidence of parenchymal kidney disease (normal U/A, proteinuria < 500 mg/d, normal renal ultrasound)

5. Absence of any other apparent cause of AKI, including shock, nephrotoxins, and infection (except peritonitis)


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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