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NOAC-VTE PROPHYLAXIS

Haematology

NOAC-VTE PROPHYLAXIS

1. Although dabigatran, rivaroxaban and apixaban are available in Australia for primary VTE prophylaxis, approval is limited to the context of elective hip and knee replacement surgery.

2. Dabigatran (150 mg and 220 mg once daily) was as effective as enoxaparin 40 mg daily at preventing any VTE and mortality of any cause, with no significant difference in major bleeding rates.

3. Rivaroxaban 10 mg daily and apixaban 2.5 mg twice daily were each superior to enoxaparin 40 mg daily with no difference in major bleeding rates.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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