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OESOPHAGEAL SCLERODERMA AND SYSTEMIC SCLEROSIS

Gastroenterology

OESOPHAGEAL SCLERODERMA AND SYSTEMIC SCLEROSIS

1. Scleroderma is the term for shiny, hard, thickened skin.

2. Scleroderma may occur alone, but when the sclerosis involves internal organs, it is called "systemic sclerosis".

3. This can be limited or diffuse in its expression.

4. Diffuse SSc is the most common connective tissue disease involving the esophagus.

5. When the esophagus is involved, the patient has very weak-to-absent esophageal peristalsis in the distal 2/3 of the esophagus. The LES is "wide open" with low or no tone or pressure, resulting in severe acid reflux damage to the esophagus.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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