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COLON CANCER-MANAGEMENT

Gastroenterology

COLON CANCER-MANAGEMENT

1. Surgical resection is the 1 st treatment option and is potentially curative.

2. Recurrences after surgery are probably due to micrometastases.

3. Adjuvant chemotherapy consists of a 5FU-based therapy.

4. Typically, 5FU plus leucovorin (LY) is used. Trials have shown benefit from oxaliplatin being added to this regimen. This protocol is called FOLFOX.

5. Adjuvant chemo is effective only for stage III or locally advanced II.

6. Radiation therapy prior to surgery is helpful for rectal lesions only.

7. Hepatic resection increases survival with solitary liver mets.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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