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AUTOIMMUNE PANCREATITIS

Gastroenterology

AUTOIMMUNE PANCREATITIS

1. 50% present with obstructive jaundice (simulating cancer of the pancreas).

2. CT can show a mass in the head of the pancreas (again simulating cancer) or diffuse enlargement (sausage-shaped pancreas).

3. There may be bile duct and pancreatic duct strictures.

4. Serum immunoglobulin-G4 (lgG4) level is usually > 2x normal.

5. Histology shows a dense lymphoplasmacytic infiltrate.

6. Treat with Prednisolone, in recurrent disease, immune-modulators may be added.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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