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CALCIUM-HYPOCALCEMIA CAUSES

Endocrinology

CALCIUM-HYPOCALCEMIA CAUSES

Most commonly:
1. Vitamin D deficiency
2. CKD - secondary hyperpara­thyroidism due to decreased renal conversion of activated Vit D.
3. Severe pancreatitis
4. Rhabdomyolysis
5. Hypomagnesemia (always check magnesium level!)
6. Hyperphosphatemia - in renal excretion of phosphorus in which calcium chelates with the phosphorus.

Less commonly:
7. Hungry bone syndrome following parathyroidectomy
8. Hypoparathyroidism
9. Pseudohypoparathyroidism
10. Citrate - used as an anticoagulant in whole blood. It chelates calcium in the serum, causing hypocalcemia after massive whole blood transfusions.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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