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THYROID CA

Endocrinology

THYROID CA

1. Papillary - most common, well-differentiated, benign.
2. Follicular - mimics normal tissue, can be well-differentiated or can progress to capsular invasion.
3. Anaplastic - malignant, death in 6 months.
4. Medullary - hyperplasia of parafollicular C cells + increased calcitonin production. 15% A/W MEN 2A/2B. MEN syndrome - overactive RET-proto-oncogene => overactive tyrosine kinase => uncontrolled cell signalling.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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