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PROLACTINOMA

Endocrinology

PROLACTINOMA

1. Most common microadenomas (<1cm).
2. Inc PRL => dec GnRH => dec LH + FSH } causes dec libido, galactorrhea (less common) in men; amenorrhea, hirsuitism, galactorrhea in women.
3. Microadenoma management - dopamine agonist (bromocriptine, cabergoline).
4. Cabergoline is contraindicated in valvular, lung or retroperitoneal fibrotic diseases.
5. Macroadenoma management, threatened vision - surgery.
6. 1/3 of macroadenomas increase in pregnancy.


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REFERENCES

1. Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
2. Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
3. Image: no reference available.

Ⓒ A. Manickam 2018

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